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Acetaminophen produces neurotoxic effects on rat brain neurons both in vitro and in vivo , its use during pregnancy is associated with teratogenic defects in testicular function and the gastrointestinal tract, and there is increased incidence of asthma in maternally exposed and postnatally exposed children

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It acts as an amylin receptor agonist, activating AMY1, AMY2, and AMY3 receptors heterodimers of the calcitonin receptor with receptor activity-modifying proteins (RAMPs) to produce satiety signaling, gastric emptying inhibition, and glucagon suppression